Cassandra Slone was born on 30 October 1981 in Tuscon, Arizona, but moved to Bloomington, Idiana at the age of two. Her start was in theater and performing arts and gradually moved over to visual arts towards her later years in school. She was asked to join the BFA program at Indiana University for printmaking and graduated in 2005.
Slone has owned her own vintage clothing store for a couple years upon finishing school and now waits tables and continues to do art. She is part of a local art group called 'Art Hospital' in Bloomington, with their own gallery and studio spaces. Her current work has revolved mostly around large collage pieces and self-portraits as a reflection on Bloomington.
Slone has said about her work "I am fully indebted to my surroundings. I typically do portrait work of people that I have known or who have affected my life in any way, good or bad. My doing portraits of people under this stipulation sometimes forces interactions that are unnatural. Having to initiate a sitting with someone who has been hurtful or even inspiring in some way can be in and of itself accomplished. It is the interaction with the person that I find most inspiring, with the portrait being almost a byproduct. I tend to do portraits in mass themed groupings, often not fully divulging the theme. In the case with the Sylvia portraits they were difficult for me to do with no real connection other than having admired some of her works."
Slone has presented a personal exhibition at SOFa Gallery, Indiana University (2005). She has mostly been involved in underground exhibits and space transformations.
Cassandra Slone currently lives and works in Bloomington, Idiana.